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OLIN-studies

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The name OLIN stands for Obstructive Lung Disease in Norrbotten. The OLIN studies include epidemiological research activities focusing on asthma, allergies, chronic bronchitis and chronic obstructive pulmonary disease (COPD) that have been carried out in Norrbotten since 1985.

Since the start in 1985, the OLIN-studies have developed from being a research project into the current extensive range of research activities with several lines of research. The OLIN studies network includes researchers from Norrbotten county council, Umeå University, Karolinska Institutet, the Sahlgrenska Academy at University of Gothenburg and Luleå University of Technology.

The studies also involve global partnerships with researchers and research groups from other countries, such as the USA, Australia, New Zealand and Vietnam, in addition to several countries in Europe. The so-called ‘FinEsS’ studies are a partnership between Finland, Estonia and Sweden which primarily concentrate on asthma, allergies and COPD. The management team and decision functions for the OLIN studies, as for the FinEsS studies, are all located in Norrbotten.

Facts about the OLIN-studies

The OLIN studies is the most successful public health and medical research project carried out so far in Norrbotten. The research includes epidemiological studies about asthma, type-1 allergies, chronic bronchitis, chronic obstructive pulmonary disease (COPD), sleep apnoea and health economics. The methods used are cross-sectional, longitudinal, case-reference and clinical studies.

In total, more than 50,000 individuals aged from 7 to 91 have participated. The OLIN studies have so far resulted in ten doctoral theses and more than 100 original and review articles. Of the ten doctoral candidates, eight are still wholly or partially active in Norrbotten. Another seven theses are partially based on OLIN data and several theses are currently being worked on.

The research started in 1985 and since then it has developed from being a research project into a comprehensive range of activities, with links to several European countries, the US, and research projects in Asia and Australia/New Zealand. In Sweden, researchers involved in the OLIN studies are also linked to teaching institutions such as Umeå University, the Sahlgrenska Academy at University of Gothenburg, Karolinska Institutet and Luleå University of Technology. The management team and decision functions are all located in Norrbotten.

Research is conducted along four lines of research:

1. Asthma and allergies among adults

2. Asthma and allergies among children

3. COPD, which also covers OSAS

4. Health economics

The overall aim of the OLIN studies is to:

  • Prevent obstructive lung diseases

In order to achieve this aim, the following areas need to be studied:

  • Prevalence and incidence of asthma, chronic obstructive pulmonary disease (COPD) and other diseases and symptoms of the respiratory tract
  • The effects of smoking, various occupational exposures and environments, including the effects of traffic and the influence of climatic factors on these diseases
  • The course of diseases, i.e. the development, involving both deterioration and improvement, and the causes of these.

26 september 2014
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